Microtubule instability driven by longitudinal and lateral strain propagation
Microtubule instability driven by longitudinal and lateral strain propagation
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Tubulin dimers associate longitudinally and laterally to form metastable microtubules (MTs). MT disassembly is preceded by subtle structural changes in tubulin fueled by GTP hydrolysis. These changes render the MT lattice unstable, but it is unclear exactly how they affect lattice energetics and strain. We performed long-time atomistic simulations...
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Full title
Microtubule instability driven by longitudinal and lateral strain propagation
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TN_cdi_plos_journals_2451547469
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2451547469
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1008132