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Microtubule instability driven by longitudinal and lateral strain propagation

Microtubule instability driven by longitudinal and lateral strain propagation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2451547469

Microtubule instability driven by longitudinal and lateral strain propagation

About this item

Full title

Microtubule instability driven by longitudinal and lateral strain propagation

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2020-09, Vol.16 (9), p.e1008132-e1008132

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Tubulin dimers associate longitudinally and laterally to form metastable microtubules (MTs). MT disassembly is preceded by subtle structural changes in tubulin fueled by GTP hydrolysis. These changes render the MT lattice unstable, but it is unclear exactly how they affect lattice energetics and strain. We performed long-time atomistic simulations...

Alternative Titles

Full title

Microtubule instability driven by longitudinal and lateral strain propagation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2451547469

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2451547469

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1008132

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