Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ
Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Renal outer medullary K+ channel, ROMK (Kir1.1, kcnj1) is expressed in the kidney and brain, but its role in the central nervous system remains unknown. Recent studies suggested an involvement of the ROMK channel in mental diseases. Tertiapin (TPN) is a European honey bee venom peptide and is reported to selectively block the ROMK channel. Here, we...
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Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ
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TN_cdi_plos_journals_2460373815
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460373815
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0233815