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Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460373815

Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

About this item

Full title

Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-11, Vol.15 (11), p.e0233815-e0233815

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Renal outer medullary K+ channel, ROMK (Kir1.1, kcnj1) is expressed in the kidney and brain, but its role in the central nervous system remains unknown. Recent studies suggested an involvement of the ROMK channel in mental diseases. Tertiapin (TPN) is a European honey bee venom peptide and is reported to selectively block the ROMK channel. Here, we...

Alternative Titles

Full title

Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2460373815

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460373815

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0233815

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