Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using drop...
Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Circulating tumor DNA (ctDNA) is released from cancer cells and oncogenic mutations in ctDNA can be measured from plasma samples. Droplet digital PCR (ddPCR) is a sensitive and specific method for the detection of mutations in ctDNA. We analyzed serial plasma samples (n = 80) from ten metastatic colorectal cancer (mCRC) patients with a known KRAS m...
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Full title
Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing
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TN_cdi_plos_journals_2464362235
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2464362235
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0239819
