In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligo...
In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Knowledge of the mechanisms of assembly of amyloid proteins into aggregates is of central importance in building an understanding of neurodegenerative disease. Given that oligomeric intermediates formed during the aggregation reaction are believed to be the major toxic species, methods to track such intermediates are clearly needed. Here we present...
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In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers
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TN_cdi_plos_journals_2479993208
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479993208
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0245548