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The coronavirus proofreading exoribonuclease mediates extensive viral recombination

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2490314871

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

About this item

Full title

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-01, Vol.17 (1), p.e1009226

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recombination is proposed to be critical for coronavirus (CoV) diversity and emergence of SARS-CoV-2 and other zoonotic CoVs. While RNA recombination is required during normal CoV replication, the mechanisms and determinants of CoV recombination are not known. CoVs encode an RNA proofreading exoribonuclease (nsp14-ExoN) that is distinct from the Co...

Alternative Titles

Full title

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2490314871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2490314871

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009226

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