K18-hACE2 mice develop respiratory disease resembling severe COVID-19
K18-hACE2 mice develop respiratory disease resembling severe COVID-19
About this item
Full title
Author / Creator
Yinda, Claude Kwe , Port, Julia R , Bushmaker, Trenton , Offei Owusu, Irene , Purushotham, Jyothi N , Avanzato, Victoria A , Fischer, Robert J , Schulz, Jonathan E , Holbrook, Myndi G , Hebner, Madison J , Rosenke, Rebecca , Thomas, Tina , Marzi, Andrea , Best, Sonja M , de Wit, Emmie , Shaia, Carl , van Doremalen, Neeltje and Munster, Vincent J
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic. Several animal models have been rapidly developed that recapitulate the asymptomatic to moderate disease spectrum. Now, there is a direct need for additional small animal models to study the pathogenesis of severe COVID-19 and for fast-tracked medical countermeasure deve...
Alternative Titles
Full title
K18-hACE2 mice develop respiratory disease resembling severe COVID-19
Authors, Artists and Contributors
Author / Creator
Port, Julia R
Bushmaker, Trenton
Offei Owusu, Irene
Purushotham, Jyothi N
Avanzato, Victoria A
Fischer, Robert J
Schulz, Jonathan E
Holbrook, Myndi G
Hebner, Madison J
Rosenke, Rebecca
Thomas, Tina
Marzi, Andrea
Best, Sonja M
de Wit, Emmie
Shaia, Carl
van Doremalen, Neeltje
Munster, Vincent J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2490315256
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2490315256
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009195