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Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian...

Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2501878207

Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian cycle

About this item

Full title

Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian cycle

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2021-02, Vol.17 (2), p.e1009350-e1009350

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The circadian clock drives extensive temporal gene expression programs controlling daily changes in behavior and physiology. In mouse liver, transcription factors dynamics, chromatin modifications, and RNA Polymerase II (PolII) activity oscillate throughout the 24-hour (24h) day, regulating the rhythmic synthesis of thousands of transcripts. Also,...

Alternative Titles

Full title

Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian cycle

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2501878207

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2501878207

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1009350

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