Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures effi...
Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient virus replication
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Author / Creator
Gao, Bo , Gong, Xiaoqian , Fang, Shouguo , Weng, Wenlian , Wang, Huan , Chu, Hongyan , Sun, Yingjie , Meng, Chunchun , Tan, Lei , Song, Cuiping , Qiu, Xusheng , Liu, Weiwei , Forlenza, Maria , Ding, Chan and Liao, Ying
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Cytoplasmic stress granules (SGs) are generally triggered by stress-induced translation arrest for storing mRNAs. Recently, it has been shown that SGs exert anti-viral functions due to their involvement in protein synthesis shut off and recruitment of innate immune signaling intermediates. The largest RNA viruses, coronaviruses, impose great threat...
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Full title
Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient virus replication
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Record Identifier
TN_cdi_plos_journals_2501882350
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2501882350
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008690
