Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody...
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A0201
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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T-cell receptor mimic (TCRm) antibodies have expanded the repertoire of antigens targetable by monoclonal antibodies, to include peptides derived from intracellular proteins that are presented by major histocompatibility complex class I (MHC-I) molecules on the cell surface. We have previously used this approach to target p53, which represents a va...
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Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A0201
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TN_cdi_plos_journals_2510586076
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2510586076
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0249967
