The structure of MgtE in the absence of magnesium provides new insights into channel gating
The structure of MgtE in the absence of magnesium provides new insights into channel gating
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Author / Creator
Jin, Fei , Sun, Minxuan , Fujii, Takashi , Yamada, Yurika , Wang, Jin , Maturana, Andrés D , Wada, Miki , Su, Shichen , Ma, Jinbiao , Takeda, Hironori , Kusakizako, Tsukasa , Tomita, Atsuhiro , Nakada-Nakura, Yoshiko , Liu, Kehong , Uemura, Tomoko , Nomura, Yayoi , Nomura, Norimichi , Ito, Koichi , Nureki, Osamu , Namba, Keiichi , Iwata, So , Yu, Ye and Hattori, Motoyuki
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed-state, and structure-based functional analyses of MgtE revealed that the binding of Mg2+ ions to the MgtE cytoplasmic domain indu...
Alternative Titles
Full title
The structure of MgtE in the absence of magnesium provides new insights into channel gating
Authors, Artists and Contributors
Author / Creator
Sun, Minxuan
Fujii, Takashi
Yamada, Yurika
Wang, Jin
Maturana, Andrés D
Wada, Miki
Su, Shichen
Ma, Jinbiao
Takeda, Hironori
Kusakizako, Tsukasa
Tomita, Atsuhiro
Nakada-Nakura, Yoshiko
Liu, Kehong
Uemura, Tomoko
Nomura, Yayoi
Nomura, Norimichi
Ito, Koichi
Nureki, Osamu
Namba, Keiichi
Iwata, So
Yu, Ye
Hattori, Motoyuki
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2528202498
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528202498
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3001231