ARID1A regulates R-loop associated DNA replication stress
ARID1A regulates R-loop associated DNA replication stress
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in about 50% of cases. While the impact of ARID1A loss on the function of the BAF chromatin remodeling...
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Full title
ARID1A regulates R-loop associated DNA replication stress
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TN_cdi_plos_journals_2528225439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528225439
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1009238
