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CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2541858087

CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

About this item

Full title

CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2021-05, Vol.17 (5), p.e1009553-e1009553

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The CBFB gene is frequently mutated in several types of solid tumors. Emerging evidence suggests that CBFB is a tumor suppressor in breast cancer. However, our understanding of the tumor suppressive function of CBFB remains incomplete. Here, we analyze genetic interactions between mutations of CBFB and other highly mutated genes in human breast can...

Alternative Titles

Full title

CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2541858087

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2541858087

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1009553

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