Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms
Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The
APOBEC3
(
A3
) genes encode cytidine deaminase proteins with potent antiviral and anti-retroelement activity. This locus is characterized by duplication, recombination, and deletion events that gave rise to the seven
A3
s found in primates. These include three single deaminase domain
A3s
(
A3A
,
A3C
, and
...
Alternative Titles
Full title
Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms
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Record Identifier
TN_cdi_plos_journals_2552289716
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552289716
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009523
