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Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated s...

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552289760

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

About this item

Full title

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-06, Vol.17 (6), p.e1009674-e1009674

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

HIV associated immune activation (IA) is associated with increased morbidity in people living with HIV (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed at reducing the HIV reservoir. The underlying mechanisms of IA have not been definitively elucidated, however, persistent production of Type I IFNs and expression of ISGs...

Alternative Titles

Full title

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2552289760

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552289760

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009674

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