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Nafamostat mesilate, a nuclear factor kappa B inhibitor, enhances the antitumor action of radiothera...

Nafamostat mesilate, a nuclear factor kappa B inhibitor, enhances the antitumor action of radiothera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2568585093

Nafamostat mesilate, a nuclear factor kappa B inhibitor, enhances the antitumor action of radiotherapy on gallbladder cancer cells

About this item

Full title

Nafamostat mesilate, a nuclear factor kappa B inhibitor, enhances the antitumor action of radiotherapy on gallbladder cancer cells

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2021-09, Vol.16 (9), p.e0257019-e0257019

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Nuclear factor kappa B (NF-κB) is a transcriptional factor that can be activated by radiotherapy and chemotherapy. The synthetic protease inhibitor nafamostat mesilate (NM) inhibits NF-κB activity and exerts antitumor actions in various types of cancer. In the present study, we hypothesized that NM might enhance the antitumor action of radiotherapy...

Alternative Titles

Full title

Nafamostat mesilate, a nuclear factor kappa B inhibitor, enhances the antitumor action of radiotherapy on gallbladder cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2568585093

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2568585093

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0257019

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