Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation with...
Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynamic pattern of glucocorticoid receptor (GR) binding at ~3,000 genomic sites in liver at the pulse pea...
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Full title
Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver
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TN_cdi_plos_journals_2573455112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2573455112
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1009737
