The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase...
The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Contents
Ebola virus (EBOV) expresses three different glycoproteins (GPs) from its GP gene. The primary product, soluble GP (sGP), is secreted in abundance during infection. EBOV sGP has been discussed as a potential pathogenicity factor, however, little is known regarding its functional role. Here, we analyzed the role of sGP in vitro and in vivo. We show...
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Full title
The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway
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TN_cdi_plos_journals_2582586577
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2582586577
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009937
