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Chromatin accessibility and gene expression during adipocyte differentiation identify context-depend...

Chromatin accessibility and gene expression during adipocyte differentiation identify context-depend...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2598100009

Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci

About this item

Full title

Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci

Publisher

San Francisco: Public Library of Science

Journal title

PLoS genetics, 2021-10, Vol.17 (10), p.e1009865-e1009865

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Chromatin accessibility and gene expression in relevant cell contexts can guide identification of regulatory elements and mechanisms at genome-wide association study (GWAS) loci. To identify regulatory elements that display differential activity across adipocyte differentiation, we performed ATAC-seq and RNA-seq in a human cell model of preadipocyt...

Alternative Titles

Full title

Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2598100009

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2598100009

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1009865

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