MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generatio...
MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data
About this item
Full title
Author / Creator
Singh, Larry N , Ennis, Brian , Loneragan, Bryn , Tsao, Noah L , Lopez Sanchez, M Isabel G , Li, Jianping , Acheampong, Patrick , Tran, Oanh , Trounce, Ian A , Zhu, Yuankun , Potluri, Prasanth , Emanuel, Beverly S , Rader, Daniel J , Arany, Zoltan , Damrauer, Scott M , Resnick, Adam C , Anderson, Stewart A , Wallace, Douglas C and Regeneron Genetics Center
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The growing number of next-generation sequencing (NGS) data presents a unique opportunity to study the combined impact of mitochondrial and nuclear-encoded genetic variation in complex disease. Mitochondrial DNA variants and in particular, heteroplasmic variants, are critical for determining human disease severity. While there are approaches for ob...
Alternative Titles
Full title
MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data
Authors, Artists and Contributors
Author / Creator
Ennis, Brian
Loneragan, Bryn
Tsao, Noah L
Lopez Sanchez, M Isabel G
Li, Jianping
Acheampong, Patrick
Tran, Oanh
Trounce, Ian A
Zhu, Yuankun
Potluri, Prasanth
Emanuel, Beverly S
Rader, Daniel J
Arany, Zoltan
Damrauer, Scott M
Resnick, Adam C
Anderson, Stewart A
Wallace, Douglas C
Regeneron Genetics Center
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2610946165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2610946165
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1009594
