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Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in S...

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in S...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2621012960

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results

About this item

Full title

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results

Publisher

United States: Public Library of Science

Journal title

PloS one, 2022-01, Vol.17 (1), p.e0262695-e0262695

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Platelet activation underpins thrombus formation in ischemic stroke. The active, dimeric form of platelet receptor glycoprotein (GP) VI plays key roles by binding platelet ligands collagen and fibrin, leading to platelet activation. We investigated whether patients presenting with stroke expressed more GPVI on their platelet surface and had more ac...

Alternative Titles

Full title

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2621012960

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2621012960

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0262695

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