A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in n...
A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The Alzheimer's brain is affected by multiple pathophysiological processes, which include a unique, organ-specific form of insulin resistance that begins early in its course. An additional complexity arises from the four-fold risk of Alzheimer's Disease (AD) in type 2 diabetics, however there is no definitive proof of causation. Several strategies...
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Full title
A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro
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TN_cdi_plos_journals_2621921471
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2621921471
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0261696
