T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival
T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival
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Author / Creator
de Mel, Sanjay , Mustafa, Nurulhuda , Selvarajan, Viknesvaran , Azaman, Muhammad Irfan , Jaynes, Patrick William , Venguidessane, Shruthi , Phuong, Hoang Mai , Alnaseri, Zubaida Talal , Phyu, The , Girard, Louis-Pierre , Chng, Wee Joo , Wardyn, Joanna , Li, Ying , An, Omer , Yang, Henry , Ng, Siok Bian and Jeyasekharan, Anand D.
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
B-cell receptor (BCR) signalling is critical for the survival of B-cell lymphomas and is a therapeutic target of drugs such as Ibrutinib. However, the role of T-cell receptor (TCR) signalling in the survival of T/Natural Killer (NK) lymphomas is not clear. ZAP-70 (zeta associated protein-70) is a cytoplasmic tyrosine kinase with a critical role in...
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Full title
T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival
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TN_cdi_plos_journals_2622772393
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2622772393
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0261469