Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody
Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The SARS coronavirus 2 (SARS-CoV-2) spike (S) protein binding to the human ACE2 receptor is the molecular event that initiates viral entry into host cells and leads to infection and virus replication. There is a need for agents blocking viral entry into host cells that are cross-reactive with emerging virus variants. VHH-72 is an anti-SARS-CoV-1 si...
Alternative Titles
Full title
Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2645449504
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2645449504
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0266250
