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MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2651150349

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

About this item

Full title

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2022-03, Vol.18 (3), p.e1010406-e1010406

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Gram-positive bacteria are protected by a thick mesh of peptidoglycan (PG) completely engulfing their cells. This PG network is the main component of the bacterial cell wall, it provides rigidity and acts as foundation for the attachment of other surface molecules. Biosynthesis of PG consumes a high amount of cellular resources and therefore requir...

Alternative Titles

Full title

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2651150349

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2651150349

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010406

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