Significant sparse polygenic risk scores across 813 traits in UK Biobank
Significant sparse polygenic risk scores across 813 traits in UK Biobank
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
We present a systematic assessment of polygenic risk score (PRS) prediction across more than 1,500 traits using genetic and phenotype data in the UK Biobank. We report 813 sparse PRS models with significant (p < 2.5 x 10-5) incremental predictive performance when compared against the covariate-only model that considers age, sex, types of genotyping...
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Full title
Significant sparse polygenic risk scores across 813 traits in UK Biobank
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TN_cdi_plos_journals_2651153341
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2651153341
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010105
