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Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normaliza...

Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normaliza...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686847670

Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines

About this item

Full title

Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2022-07, Vol.17 (7), p.e0271245-e0271245

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

The prognosis of the patients with inoperable or advanced granulosa cell tumors (GCTs) is still poor, and therefore it is important to establish a novel treatment strategy. Here we investigated the in vitro effects of a histone deacetylase inhibitor, panobinostat (PS) on two GCT cell lines (KGN and COV434). GCT cell lines were found to be susceptib...

Alternative Titles

Full title

Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2686847670

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2686847670

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0271245

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