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A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT...

A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2719396982

A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT)

About this item

Full title

A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT)

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2022-09, Vol.17 (9), p.e0271304

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

We hypothesized that a drug's clinical signature (or phenotype) of liver injury can be assessed and used to quantitatively develop a computer-assisted DILI causality assessment-tool (DILI-CAT). Therefore, we evaluated drug-specific DILI-phenotypes for amoxicillin-clavulanate (AMX/CLA), cefazolin, cyproterone, and Polygonum multiflorum using data fr...

Alternative Titles

Full title

A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2719396982

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2719396982

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0271304

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