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Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2725273649

Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

About this item

Full title

Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2022-09, Vol.18 (9), p.e1010436

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Ferroptosis is an iron-dependent form of regulated cell death associated with uncontrolled membrane lipid peroxidation and destruction. Previously, we showed that dietary dihomo-gamma-linolenic acid (DGLA; 20: 3(n-6)) triggers ferroptosis in the germ cells of the model organism, Caenorhabditis elegans. We also demonstrated that ether lipid-deficien...

Alternative Titles

Full title

Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2725273649

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2725273649

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1010436

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