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LRRC15 inhibits SARS-CoV-2 cellular entry in trans

LRRC15 inhibits SARS-CoV-2 cellular entry in trans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2737135828

LRRC15 inhibits SARS-CoV-2 cellular entry in trans

About this item

Full title

LRRC15 inhibits SARS-CoV-2 cellular entry in trans

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2022-10, Vol.20 (10), p.e3001805

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is mediated by the entry receptor angiotensin-converting enzyme 2 (ACE2). Although attachment factors and coreceptors facilitating entry are extensively studied, cellular entry factors inhibiting viral entry are largely unknown. Using a
surface
ome CRISPR activation screen...

Alternative Titles

Full title

LRRC15 inhibits SARS-CoV-2 cellular entry in trans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2737135828

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2737135828

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3001805

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