Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic ar...
Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Diabetes mellitus is a chronic metabolic disorder which induces endothelial dysfunction and platelet activation. Eicosanoids produced from arachidonic acid regulate cellular and vascular functions. Sigma-1 receptors (S1R) are expressed in platelets and endothelial cells and S1R expression is protective in diabetes.
Our aim was to examine the inf...
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Full title
Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats
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TN_cdi_plos_journals_2737407849
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2737407849
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0265854
