Profiling transcription factor activity dynamics using intronic reads in time-series transcriptome d...
Profiling transcription factor activity dynamics using intronic reads in time-series transcriptome data
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Author / Creator
Wu, Yan , Xue, Lingfeng , Huang, Wen , Deng, Minghua and Lin, Yihan
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Activities of transcription factors (TFs) are temporally modulated to regulate dynamic cellular processes, including development, homeostasis, and disease. Recent developments of bioinformatic tools have enabled the analysis of TF activities using transcriptome data. However, because these methods typically use exon-based target expression levels,...
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Full title
Profiling transcription factor activity dynamics using intronic reads in time-series transcriptome data
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TN_cdi_plos_journals_2762184196
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2762184196
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1009762