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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding le...

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding le...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2762201678

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

About this item

Full title

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2022-01, Vol.18 (1), p.e1010226-e1010226

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The complement system is a first-line innate host immune defence against invading pathogens. It is activated via three pathways, termed Classical, Lectin and Alternative, which are mediated by antibodies, carbohydrate arrays or microbial liposaccharides, respectively. The three complement pathways converge in the formation of C3-convertase followed...

Alternative Titles

Full title

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2762201678

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2762201678

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1010226

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