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Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
Author / Creator:Cwiklinski, Krystyna ; Robinson, Mark W. ; Donnelly, Sheila ; Dalton, John P.
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2021-01, Vol.22 (1), p.46-46, Article 46
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The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
Author / Creator:Cwiklinski, Krystyna ; Dalton, John Pius ; Dufresne, Philippe J ; La Course, James ; Williams, Diana Jl ; Hodgkinson, Jane ; Paterson, Steve
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2015-04, Vol.16, p.71-71
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Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses
Author / Creator:Tran, Nham ; Ricafrente, Alison ; To, Joyce ; Lund, Maria ; Marques, Tania M. ; Gama-Carvalho, Margarida ; Cwiklinski, Krystyna ; Dalton, John P. ; Donnelly, Sheila
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-03, Vol.11 (1), p.6712-6712, Article 6712
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Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)
Author / Creator:Mathew, Rency ; Wunderlich, Juliane ; Thivierge, Karine ; Cwiklinski, Krystyna ; Dumont, Claire ; Tilley, Leann ; Rohrbach, Petra ; Dalton, John P.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-02, Vol.11 (1), p.2854-2854, Article 2854
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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins
Author / Creator:De Marco Verissimo, Carolina ; Jewhurst, Heather L. ; Dobó, József ; Gál, Péter ; Dalton, John P. ; Cwiklinski, Krystyna
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-01, Vol.18 (1), p.e1010226-e1010226
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An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica
Author / Creator:Smith, David ; Cwiklinski, Krystyna ; Jewhurst, Heather ; Tikhonova, Irina G. ; Dalton, John P.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-11, Vol.10 (1), p.20657-20657, Article 20657
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Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatic...
Author / Creator:Ricafrente, Alison ; Cwiklinski, Krystyna ; Nguyen, Hieu ; Dalton, John P. ; Tran, Nham ; Donnelly, Sheila
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2022-06, Vol.23 (1), p.419-419, Article 419
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Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells
Author / Creator:de la Torre-Escudero, Eduardo ; Gerlach, Jared Q. ; Bennett, Adam P. S. ; Cwiklinski, Krystyna ; Jewhurst, Heather L. ; Huson, Kathryn M. ; Joshi, Lokesh ; Kilcoyne, Michelle ; O’Neill, Sandra ; Dalton, John P. ; Robinson, Mark W.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-01, Vol.13 (1), p.e0007087-e0007087
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Exploring the utility of circulating miRNAs as diagnostic biomarkers of fasciolosis
Author / Creator:Chowdhury, Sumaiya ; Ricafrente, Alison ; Cwiklinski, Krystyna ; Sais, Dayna ; Dalton, John P. ; Tran, Nham ; Donnelly, Sheila
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-03, Vol.14 (1), p.7431-7431, Article 7431
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Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity
Author / Creator:Murphy, Anna ; Cwiklinski, Krystyna ; Lalor, Richard ; O’Connell, Barry ; Robinson, Mark W. ; Gerlach, Jared ; Joshi, Lokesh ; Kilcoyne, Michelle ; Dalton, John P. ; O’Neill, Sandra M.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2020-09, Vol.14 (9), p.e0008626
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Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling
Author / Creator:Vorel, Jiří ; Cwiklinski, Krystyna ; Roudnický, Pavel ; Ilgová, Jana ; Jedličková, Lucie ; Dalton, John P. ; Mikeš, Libor ; Gelnar, Milan ; Kašný, Martin
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2021-04, Vol.22 (1), p.274-274, Article 274
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A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance
Author / Creator:Beesley, Nicola J. ; Cwiklinski, Krystyna ; Allen, Katherine ; Hoyle, Rebecca C. ; Spithill, Terry W. ; La Course, E. James ; Williams, Diana J. L. ; Paterson, Steve ; Hodgkinson, Jane E.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-01, Vol.19 (1), p.e1011081
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Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases
Author / Creator:De Marco Verissimo, Carolina ; Jewhurst, Heather L. ; Tikhonova, Irina G. ; Urbanus, Rolf T. ; Maule, Aaron G. ; Dalton, John P. ; Cwiklinski, Krystyna
Publisher:San Francisco: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2020-08, Vol.14 (8), p.e0008510-e0008510
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Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts
Author / Creator:Zhang, Xiao-Xuan ; Cwiklinski, Krystyna ; Hu, Rui-Si ; Zheng, Wen-Bin ; Sheng, Zhao-An ; Zhang, Fu-Kai ; Elsheikha, Hany M. ; Dalton, John P. ; Zhu, Xing-Quan
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2019-10, Vol.20 (1), p.729-729, Article 729
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Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica
Author / Creator:Ruiz-Campillo, Maria Teresa ; Molina Hernandez, Veronica ; Escamilla, Alejandro ; Stevenson, Michael ; Perez, Jose ; Martinez-Moreno, Alvaro ; Donnelly, Sheila ; Dalton, John P. ; Cwiklinski, Krystyna
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-06, Vol.7 (1), p.2782-14, Article 2782
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Proteomics of Host-Helminth Interactions
Author / Creator:Robinson, Mark W. ; Cwiklinski, Krystyna
Publisher:Basel: MDPI AG
Journal title:Pathogens (Basel), 2021-10, Vol.10 (10), p.1317
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Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during...
Author / Creator:Calvani, Nichola Eliza Davies ; De Marco Verissimo, Carolina ; Jewhurst, Heather Louise ; Cwiklinski, Krystyna ; Flaus, Andrew ; Dalton, John Pius
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2022-09, Vol.11 (10), p.1968
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Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans
Author / Creator:Garcia-Campos, Andres ; Ravidà, Alessandra ; Nguyen, D. Linh ; Cwiklinski, Krystyna ; Dalton, John P. ; Hokke, Cornelis H. ; O’Neill, Sandra ; Mulcahy, Grace
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2016-05, Vol.10 (5), p.e0004688-e0004688
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Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)
Author / Creator:Shiels, Jenna ; Cwiklinski, Krystyna ; Alvarado, Raquel ; Thivierge, Karine ; Cotton, Sophie ; Gonzales Santana, Bibiana ; To, Joyce ; Donnelly, Sheila ; Taggart, Clifford C. ; Weldon, Sinead ; Dalton, John P.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2020-07, Vol.14 (7), p.e0008470-e0008470
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The Zoonotic Helminth Parasite Fasciola hepatica: Virulence-Associated Cathepsin B and Cathepsin L Cysteine Peptidases Secreted by Infective Newly Excysted Juveniles (NEJ)
Author / Creator:Barbour, Tara ; Cwiklinski, Krystyna ; Lalor, Richard ; Dalton, John Pius ; De Marco Verissimo, Carolina
Publisher:Switzerland: MDPI AG
Journal title:Animals (Basel), 2021-12, Vol.11 (12), p.3495
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Showing 1 to 20 of 36 results

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Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver

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The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution

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Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses

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Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)

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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

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An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica

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Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatic...

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Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

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Exploring the utility of circulating miRNAs as diagnostic biomarkers of fasciolosis

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Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity

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Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling

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A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance

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Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases

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Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts

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Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica

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Proteomics of Host-Helminth Interactions

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Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during...

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Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans

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Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)

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The Zoonotic Helminth Parasite Fasciola hepatica: Virulence-Associated Cathepsin B and Cathepsin L Cysteine Peptidases Secreted by Infective Newly Excysted Juveniles (NEJ)

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