Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protoc...
Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Satisfactory treatment is often lacking for spasticity, a highly prevalent motor disorder in patients with spinal cord injury (SCI). Low concentrations of riluzole potently reduce the persistent sodium current, the post-SCI increase in which contributes to spasticity. The repurposing of this drug may therefore constitute a useful potential therapeu...
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Full title
Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial
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TN_cdi_plos_journals_2767424732
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2767424732
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0276892
