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Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2777440686

Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

About this item

Full title

Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2023-01, Vol.19 (1), p.e1010847-e1010847

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mutations in LRRK2 are the most common genetic cause of Parkinson's disease. Despite substantial research efforts, the physiological and pathological role of this multidomain protein remains poorly defined. In this study, we used a systematic approach to construct the general protein-protein interactome around LRRK2, which was then evaluated taking...

Alternative Titles

Full title

Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2777440686

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2777440686

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1010847

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