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A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctio...

A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2802052788

A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus

About this item

Full title

A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2023-03, Vol.17 (3), p.e0010905-e0010905

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Assessment of cellular immune responses by combining intracellular cytokine staining and immunophenotyping using flow cytometry enables the simultaneous measurement of T cell phenotype and effector function in response to pathogens and vaccines. The use of whole blood samples rather than peripheral blood mononuclear cells avoids both the need for i...

Alternative Titles

Full title

A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2802052788

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2802052788

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0010905

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