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The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromat...

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2802053484

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

About this item

Full title

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2023-03, Vol.19 (3), p.e1010656

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

DND1 is essential to maintain germ cell identity. Loss of Dnd1 function results in germ cell differentiation to teratomas in some inbred strains of mice or to somatic fates in zebrafish. Using our knock-in mouse line in which a functional fusion protein between DND1 and GFP is expressed from the endogenous locus (Dnd1GFP), we distinguished two male...

Alternative Titles

Full title

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2802053484

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2802053484

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1010656

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