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Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer's...

Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer's...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2802054000

Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer's disease

About this item

Full title

Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer's disease

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2023-03, Vol.19 (3), p.e1010681-e1010681

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Neurofibrillary lesions composed of tau protein aggregates are defining hallmarks of Alzheimer's Disease. Despite tau filaments appearing to spread between networked brain regions in a prion-like manner, certain areas including cerebellum resist trans-synaptic spread of tauopathy and degeneration of their constituent neuronal cell bodies. To identi...

Alternative Titles

Full title

Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer's disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2802054000

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2802054000

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1010681

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