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Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterati...

Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2803893740

Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney

About this item

Full title

Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney

Publisher

United States: Public Library of Science

Journal title

PloS one, 2023-04, Vol.18 (4), p.e0284562-e0284562

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Nephrotoxicity is an important drug safety aspect to be assessed during drug discovery and development. To study renal toxicity,
in vitro
cell-based assays are often used. Unfortunately, translating the results of such cell assays to vertebrates including human remains challenging. Therefore, we aim to evaluate whether zebrafish larvae (ZFL)...

Alternative Titles

Full title

Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2803893740

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2803893740

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0284562

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