Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-media...
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis
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Author / Creator
Wang, Xinli , Wei, Xuxia , Lu, Yan , Wang, Qinghuan , Fu, Rong , Wang, Yin , Wang, Qin , Wang, Xiangyan , Chen, Shangwu , Xu, Anlong and Yuan, Shaochun
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Members of the gasdermin (GSDM) family are pore-forming effectors that cause membrane permeabilization and pyroptosis, a lytic proinflammatory type of cell death. To reveal the functional evolution of GSDM-mediated pyroptosis at the transition from invertebrates to vertebrates, we conducted functional characterization of amphioxus GSDME (BbGSDME) a...
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Full title
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis
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TN_cdi_plos_journals_2826804200
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2826804200
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002062