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Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-media...

Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-media...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2826804200

Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis

About this item

Full title

Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2023-05, Vol.21 (5), p.e3002062-e3002062

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Members of the gasdermin (GSDM) family are pore-forming effectors that cause membrane permeabilization and pyroptosis, a lytic proinflammatory type of cell death. To reveal the functional evolution of GSDM-mediated pyroptosis at the transition from invertebrates to vertebrates, we conducted functional characterization of amphioxus GSDME (BbGSDME) a...

Alternative Titles

Full title

Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2826804200

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2826804200

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3002062

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