Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exha...
Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The oncolytic autonomous parvovirus Minute Virus of Mice (MVM) establishes infection in the nuclear environment by usurping host DNA damage signaling proteins in the vicinity of cellular DNA break sites. MVM replication induces a global cellular DNA Damage Response (DDR) that is dependent on signaling by the ATM kinase and inactivates the cellular...
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Full title
Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion
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TN_cdi_plos_journals_2826806081
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2826806081
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1011203
