A mutation-level covariate model for mutational signatures
A mutation-level covariate model for mutational signatures
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Mutational processes and their exposures in particular genomes are key to our understanding of how these genomes are shaped. However, current analyses assume that these processes are uniformly active across the genome without accounting for potential covariates such as strand or genomic region that could impact such activities. Here we suggest the...
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Full title
A mutation-level covariate model for mutational signatures
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TN_cdi_plos_journals_2838334735
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2838334735
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1011195