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Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regula...

Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regula...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2838334893

Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regulatory B cells

About this item

Full title

Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regulatory B cells

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2023-06, Vol.17 (6), p.e0011344-e0011344

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

During chronic schistosome infections, a complex regulatory network is induced to regulate the host immune system, in which IL-10-producing regulatory B (Breg) cells play a significant role. Schistosoma mansoni soluble egg antigens (SEA) are bound and internalized by B cells and induce both human and mouse IL-10 producing Breg cells. To identify Br...

Alternative Titles

Full title

Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regulatory B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2838334893

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2838334893

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0011344

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