Molecular insights into the inhibitory potential of anthocyanidins on glucokinase regulatory protein
Molecular insights into the inhibitory potential of anthocyanidins on glucokinase regulatory protein
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Computational methods were used to investigate six anthocyanidins exhibiting antidiabetic activity by inhibiting glucokinase regulatory protein (GKRP) activity. Density functional theory was used to optimise the geometry of anthocyanidins and calculate their quantum chemical properties. A blind docking method was employed to conduct a molecular doc...
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Full title
Molecular insights into the inhibitory potential of anthocyanidins on glucokinase regulatory protein
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TN_cdi_plos_journals_2839720376
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2839720376
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0288810
