Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isofo...
Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
PTEN is a major tumor suppressor gene frequently mutated in human tumors, and germline PTEN gene mutations are the molecular diagnostic of PTEN Hamartoma Tumor Syndrome (PHTS), a heterogeneous disorder that manifests with multiple hamartomas, cancer predisposition, and neurodevelopmental alterations. A diversity of translational and splicing PTEN i...
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Full title
Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants
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TN_cdi_plos_journals_2844636440
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2844636440
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0289369
