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NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory fa...

NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory fa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2851961227

NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3

About this item

Full title

NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2023-07, Vol.19 (7), p.e1011511-e1011511

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The innate immune system is the first line of the host's defense, and studying the mechanisms of the negative regulation of interferon (IFN) signaling is important for maintaining the balance of innate immune responses. Here, we found that the host GTP-binding protein 4 (NOG1) is a negative regulator of innate immune responses. Overexpression of NO...

Alternative Titles

Full title

NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2851961227

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2851961227

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1011511

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