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Regularized sequence-context mutational trees capture variation in mutation rates across the human g...

Regularized sequence-context mutational trees capture variation in mutation rates across the human g...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2851974458

Regularized sequence-context mutational trees capture variation in mutation rates across the human genome

About this item

Full title

Regularized sequence-context mutational trees capture variation in mutation rates across the human genome

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2023-07, Vol.19 (7), p.e1010807

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Germline mutation is the mechanism by which genetic variation in a population is created. Inferences derived from mutation rate models are fundamental to many population genetics methods. Previous models have demonstrated that nucleotides flanking polymorphic sites-the local sequence context-explain variation in the probability that a site is polym...

Alternative Titles

Full title

Regularized sequence-context mutational trees capture variation in mutation rates across the human genome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2851974458

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2851974458

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1010807

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