Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potent...
Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potential new treatment route for amyotrophic lateral sclerosis
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Contents
Riluzole is the only treatment known to improve survival in patients with Amyotrophic Lateral Sclerosis (ALS). However, oral riluzole efficacy is modest at best, further it is known to have large inter-individual variability of serum concentration and clearance, is formulated as an oral drug in a patient population plagued with dysphagia, and has k...
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Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potential new treatment route for amyotrophic lateral sclerosis
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TN_cdi_plos_journals_2854906689
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2854906689
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0277718
