rRNA transcription is integral to phase separation and maintenance of nucleolar structure
rRNA transcription is integral to phase separation and maintenance of nucleolar structure
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Publisher
San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
Transcription of ribosomal RNA (rRNA) by RNA Polymerase (Pol) I in the nucleolus is necessary for ribosome biogenesis, which is intimately tied to cell growth and proliferation. Perturbation of ribosome biogenesis results in tissue specific disorders termed ribosomopathies in association with alterations in nucleolar structure. However, how rRNA tr...
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Full title
rRNA transcription is integral to phase separation and maintenance of nucleolar structure
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TN_cdi_plos_journals_2865506050
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2865506050
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010854
