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Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice inform...

Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice inform...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069178959

Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation

About this item

Full title

Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2023-10, Vol.19 (10), p.e1010997-e1010997

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Diet-related metabolic syndrome is the largest contributor to adverse health in the United States. However, the study of gene-environment interactions and their epigenomic and transcriptomic integration is complicated by the lack of environmental and genetic control in humans that is possible in mouse models. Here we exposed three mouse strains, C5...

Alternative Titles

Full title

Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069178959

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069178959

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1010997

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